Job Requirements: M.Sc. or higher Degree in Computer Science
Modified DNA bases play an important epigenetic role in the regulation of gene expression in development and disease. In mammals there are four different cytidine modifications in genomic DNA known to have an epigenetic function, most prominently 5-hydroxymethylcotosine. There are many more known DNA modifications, whose function remain unknown and await characterization, including of the cellular enzymes that affect these modifications, which will be the aim of the project. Our lab has a broad expertise not only in molecular cell biology and bioinformatics, but in bioanalytical chemistry, where we are using LC/MS/MS detection for modified nucleobases. Beyond mass spectrometry analysis, we will knockout candidate genes in mouse embryonic stem cells (mESCs) by the CRISPR/Cas9 genome editing technique and analyze the physiological relevance of these genes in pluripotency and during mESC in vitro differentiation by e.g. RNA sequencing. Given the biological importance of the new DNA modification, the project promises to be ground breaking, opening unexplored fields in epigenetics. This PhD project will be particularly suited for students with interest in biochemistry and/or bioorganic analytical methods, particularly mass spectrometry. [More]
We are looking for a motivated candidate with an academic background and an interest in developing the skills to manage projects independently. The role requires creative thinking, excellent developer and communication skills in an international environment and a ‘can-do’ philosophy. You will contribute to the planning and development of an integrative single entry point solution for 13 European research infrastructures to offer access to their resources in a cross-platform model. You will co-ordinate with both the developer of the Instruct web-based systems and the technical teams of other related projects. [More]
The Department of Molecular and Biomedical Sciences at the University of Maine is seeking to fill a tenure-track position at the Assistant Professor level in the area of Bioinformatics/Computational Biology. The successful applicant will establish and lead a productive research program in the areas of bioinformatics/computational biology that provides research...more... [More]
Bachelor of Science in Computer Science, Computer Engineering, Electrical Engineering or related field and at least 5 years of professional full time developer... From Synthetic Genomics, Inc. - 15 Apr 2016 22:44:14 GMT - View all La Jolla jobs [More]
Perform machine learning, natural language, and statistical analysis methods, such as classification, collaborative filtering, association rules, sentiment... From KPMG LLP - 14 Apr 2016 08:23:27 GMT - View all New York jobs [More]
Perform machine learning, natural language, and statistical analysis methods, such as classification, collaborative filtering, association rules, sentiment... From KPMG LLP - 14 Apr 2016 08:23:27 GMT - View all New York jobs [More]
And bioinformatics is preferred. The names and contact information for three references. Responsibilities for this position include, but are not limited to,... From Marine Biological Laboratory - 14 Apr 2016 21:18:53 GMT - View all Woods Hole jobs [More]
And bioinformatic analysis. (4) The names and contact information for three references. Applicants should have a B.A./B.S., or M.A/M.S.... From Marine Biological Laboratory - 14 Apr 2016 21:21:11 GMT - View all Woods Hole jobs [More]
And a data system effort to establish a public bioinformatics repository and collaborative analysis software platform.... From QTS - 13 Apr 2016 04:08:01 GMT - View all Mountain View jobs [More]
Conduct User Research and analysis to understand users, tasks, contexts and unmet needs. DNAnexus combines expertise in cloud computing and bioinformatics to... From DNAnexus - 15 Apr 2016 22:50:36 GMT - View all Mountain View jobs [More]