Bioinformatics Postdoctoral Associate

Job ID: 679487
Job date: 2019-03-29
End Date: 2019-05-28

Company : Sanford-Burnham Medical Research Institute 

Country : United States 

Role : Postdoc 


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Job Description:
A postdoctoral associate opening is available in the laboratory of Alexey Terskikh at the Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California. SBP is a preeminent, independent biomedical research institute dedicated to understanding human biology and disease, and advancing scientific discoveries to profoundly impact human health. For over 40 years, our research has produced breakthroughs in cancer, neuroscience, immunology and children’s diseases, and is anchored by our NCI-designated cancer center and advanced drug discovery capabilities.


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Additional Info:
The Terskikh laboratory is thriving is at the intersection of neurogenesis (including neural crest and adult hippocampal neurogenesis), brain cancer (glioblastoma), and epigenetic regulation. We have established mouse models of adult neurogenesis using conditional ablation of SOX2 and primary cilia (Shh signaling) in radial glia stem cells and developed a novel platform for microscopic imaging of epigenetic landscape (MIEL) in single cells. MIEL uses advanced imaging and machine learning to investigate the change of epigenetic signatures during cell differentiation and upon exposure to the environment, including the high throughput drug screening format. The lab has also established a pipeline for hair follicle regeneration using human induced pluripotent stem cells. The Postdoctoral Associate will be developing his/her own project while supporting several ongoing projects in the laboratory through automating information and analysis pipelines, data integration, pattern-matching analyses and visualization of a variety of different data sets, including single cell sequencing, bulk NGS, ChIP-Seq, Nuc-Seq, ATAC-Seq, and proteomics.

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