Bioinformatics Scientist, Cancer Genomics

Job ID: 384601362
Job date: 2017-07-01
End Date:

Company : New York Genome Center 

Country :

Role : Research Scientist 


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Job Description:
The New York Genome Center is looking for a highly motivated individual to join our computational biology group. As Bioinformatics Scientist, you will be responsible for handling of custom analysis and reporting for NYGC staff and collaborators. You will also share technical responsibility for the maintenance, benchmarking, and continuous improvement of our cancer genome analysis pipelines. You will collaborate with analysts and programmers performing development and analysis in this area. You should have significant experience in cancer genomics, including familiarity with commonly used algorithms for alignment, variant calling, and structural variant calling. Expertise in one or more common disease areas would be ideal. Collaboration with other members of the computational biology team as well as external collaborators and customers is paramount. Examples of recent projects involve tumor evolution, tumor heterogeneity, liquid biopsy, and prediction of personalized treatments (such as targeted therapies or immunotherapy). Publication of developed methods and scientific findings is encouraged.

Job duties will include, but may not be limited to:

  • Contribute to setup, management and maintenance of next generation sequencing (NGS) data analysis pipelines
  • Analyze sequencing data using the established pipeline(s)
  • Stay current on innovations in DNA sequencing analysis
  • Develop and implement innovative computational approaches for the analysis of large sequence datasets from NGS technologies
  • Collaborate and consult with external and internal researchers on the analyses of NGS data
  • Interpret and present the results of the computational and statistical analyses to collaborators and coworkers
  • Work with the software engineering team to ensure pipeline upgrades and new pipelines are properly implemented in our production workflow manager
  • Assist collaborators with data access, analysis, and interpretation
  • Supervise and guide bioinformatics analysts/programmers
  • Participate in grant application writing
  • Publish results in scientific journals and give presentations at conferences.
Required Skills:
    PhD. in bioinformatics, computational biology, genetics, computer science or similar
  • 3 or more years work experience in Bioinformatics and Genomics with experience in cancer genomics
  • Experience managing and working with next generation sequencing data required
  • Extensive knowledge and experience in the use of existing bioinformatics tools and biological databases, as well as familiarity with cloud computing required
  • Proficiency in python and R required, and one or more programming languages such as Perl, Java, or C/C++ desirable, as well as willingness to learn new programming languages as necessary to collaborate at NYGC
  • Experience working in Linux and running tasks in a cluster environment (e.g. SGE) required
  • Experience working in teams centered around a biological question and with external collaborators required
  • Excellent written and verbal communication skills required
  • Experience with design of sequence analysis algorithms desirable.


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Additional Info:
The New York Genome Center (NYGC) is at the forefront of transforming biomedical research and clinical care with the mission of saving lives. Comprised of renowned academic, medical and industry leaders across the globe, NYGC focuses on translating genomic research into clinical solutions for serious disease. Our member organizations are united in this unprecedented collaboration of technology, science, and medicine.

We implement advanced genomic research, and integrate our findings with world-class technologies and physician-scientists in order to help solve diseases. We harness the diversity of New York’s institutions and people to drive scientific discoveries that will vastly improve clinical care — ethically, equitably and urgently.

We advocate and educate, sharing our findings with the global scientific, medical and thought leadership communities to broaden the reach of the New York Genome Center to help patients in every corner of the world. We create synergies through collaboration to continually innovate and advance our vision.

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