Bioinformatics Scientist (DSP-NGS)

Job ID:
Job date: 2017-10-07
End Date:

Company : Nanostring Technologies 

Country :

Role : Research Scientist 


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Job Description:
NanoString is seeking a talented and highly motivated Bioinformatics Scientist/Developer to join our Research & Development group. S/he will join an energetic and collaborative team working to integrate next-generation sequencing (NGS) platforms into our novel Digital Spatial Profiling (DSP) technology. An ideal candidate will enjoy playing a leading role at the interface between NGS scientists and commercial software and test engineers.

Essential Duties:

  • Development of NGS algorithms and secondary analysis pipelines, with a focus on the Illumina platform
  • Design and develop pipelines and software that solves the problem at hand with an eye toward performance, extendibility and maintainability
  • Work closely with bench scientists to adapt NGS pipelines to experimental parameters, with deep understanding of the impact of upstream library preparations workflows on downstream data processing and analysis
  • Work closely with software engineers and QA to convert prototype algorithms into software in accordance with NanoString’s ISO 13485 and IEC 62304 quality system procedures to ensure the quality and robustness of all customer-facing and internal software
  • Thoroughly document pipelines, requirements, architecture, and design of software systems with clear and concise language as well as reviewing and providing insightful feedback on documentation
  • Maintain rigorous quality and performance standards
Requirements:
  • Bachelor of Science degree or higher in bioinformatics, computational biology, computer science or related field
  • 4+ years of combined industry and post-doctoral work experience in NGS software and pipeline development and analysis (M.S. with 7+ years of relevant work experience will be considered)
  • Experience designing and building flexible NGS pipelines for broad or commercial utility
  • Understanding of end-to-end NGS workflows, from NGS library prep and QC to NGS data file outputs (i.e. FASTQ)
  • Experience with common NGS bioinformatic tools (e.g. Bowtie, SAMTools), R and/or Python, LINUX shell scripting
  • Excellent problem solving, troubleshooting, and communication skills
  • Preferred experience designing and developing commercial SW applications, including creating software architecture documents, requirements, design documents, test protocols, operating procedures, project plans, estimations, risk analysis worksheets, etc.
  • Preferred experience in creating and executing manual and automated unit tests
Additional Experience Desired:
  • Experience with Amazon AWS, Docker Containers
  • Cybersecurity and/or mobile development background
  • Web development experience with Angular and Bootstrap frameworks
  • Work with Microsoft TFS for ALM including version control/configuration management.
  • Experience using MVC design pattern with Visual Studio 2017 using .NET Core
  • Experience working in an ISO 62304, ISO 13485, or ISO 9001 qualified organization


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Additional Info:
NanoString is an EOE

NanoString participates in E-Verify. E-Verify is a web-based system that allows an employer to determine an employee's eligibility to work in the US using information reported on an employee's Form I-9. The E-Verify system confirms eligibility with both the Social Security Administration (SSA) and Department of Homeland Security (DHS). For more information, please go to the USCIS E-Verify website.

[Click Here to Access the Original Job Post]