Job ID: 18765
Job date: 2018-04-17
End Date:
Company : Children s Hospital of Philadelphia Country : Role : Research Scientist
Job date: 2018-04-17
End Date:
Company : Children s Hospital of Philadelphia Country : Role : Research Scientist
Job Description:
The Bioinformatics Scientist I position is an entry-level position for a non-PhD level professional. The focus of the position is tailored analysis of genetic data and other complex molecular data types to collaboratively support researchers in the Maris Laboratory at CHOP. Dr. Maris leads a multi-disciplinary translational pediatric oncology research program, which uses integrative genomics to move rational treatment therapies to the clinic. The candidate will support the lab’s bioinformatics initiatives, implement and modify existing algorithms, and execute routine tasks within the general area of bioinformatics analysis. All activities occur with a moderate to high degree of supervision and the individual will also rely on some peer-to-peer mentorship. The Bioinformatics Scientist I will be primarily focused on the support of senior computational scientists within the Maris Lab, and may have direct interaction with collaborators and investigators to work on translational and research projects. Job Responsibilities: Data Analysis (20%): Analyzes data of high complexity by applying sound statistical and commonly accepted bioinformatics methods to -omics data under supervision of mentors and peers.
Additional Info:
Req ID: 18765 Shift: Days Employment Status: AF - Active - Regular - Full Time All CHOP employees who work in a patient building or who provide patient care are required to receive an annual influenza vaccine unless they are granted a medical or religious exemption. Children's Hospital of Philadelphia is committed to providing a safe and healthy environment for its patients, family members, visitors and employees. In an effort to achieve this goal, employment at Children's Hospital of Philadelphia, other than for positions with regularly scheduled hours in New Jersey, is contingent upon an attestation that the job applicant does not use tobacco products or nicotine in any form and a negative nicotine screen (the latter occurs after a job offer). Children's Hospital of Philadelphia is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability or protected veteran status. VEVRAA Federal Contractor/Seeking priority referrals for protected veterans. Please contact our hiring official with any referrals or questions. CHOP Careers Contact Talent Acquisition 2716 South Street, 6th Floor Philadelphia, PA 19146 Phone: 866-820-9288 Email: TalentAcquisition@email.chop.edu[Click Here to Access the Original Job Post]
The Bioinformatics Scientist I position is an entry-level position for a non-PhD level professional. The focus of the position is tailored analysis of genetic data and other complex molecular data types to collaboratively support researchers in the Maris Laboratory at CHOP. Dr. Maris leads a multi-disciplinary translational pediatric oncology research program, which uses integrative genomics to move rational treatment therapies to the clinic. The candidate will support the lab’s bioinformatics initiatives, implement and modify existing algorithms, and execute routine tasks within the general area of bioinformatics analysis. All activities occur with a moderate to high degree of supervision and the individual will also rely on some peer-to-peer mentorship. The Bioinformatics Scientist I will be primarily focused on the support of senior computational scientists within the Maris Lab, and may have direct interaction with collaborators and investigators to work on translational and research projects. Job Responsibilities: Data Analysis (20%): Analyzes data of high complexity by applying sound statistical and commonly accepted bioinformatics methods to -omics data under supervision of mentors and peers.
- Works with Dr Maris’ research investigators to analyze multi-omics data.
- Stays current with evolving algorithms and methods of NGS analysis.
- Stays current with biological databases, tools, and resources to help annotate and prioritize variants and genetic lesions.
- Integrative analysis of multiple data types, genomic, phenotype, annotation etc…
- Statistical analysis and machine learning on data to support hypothesis-driven or data-driven research.
- Gathering, summarizing, and visualization of genomic or other types of biological data.
- Strong knowledge of biological entities and concepts to accelerate the research process.
- Implements, maintains, and regularly contributes to formal and bioinformatics group-centralized code management system.
- Continually keeps abreast of evolving data generation platform fundamentals, file-specific information representation, and strategic application of code base to optimize value of data.
- Adopts appropriate forking and other strategies for robust code development. Apply to general bioinformatics group code base.
- Adopts best practices for code development consistent with larger bioinformatics group. This includes choice of language based on the type of solution being developed, the likely life cycle and downstream usage of the resulting application, and integration with other systems.
- Ensures that all routinely used tools (e.g. those included in shared analysis pipelines) are versioned and managed through a source control system.
- Ensures that configuration files that provide parameters to algorithms and analysis software are versioned and managed through a source control system.
- Develops and implements automated data-driven testing processes that test reproducibility of results between versions of pipeline software.
- Develops and implements automated deployment processes that build and configure systems from source control repositories, eliminating the need to manually modify configuration files.
- Attends group and team meetings and contributes primarily factual information regarding processes and approach.
- Provides bioinformatics domain expertise and potentially prototypes to software engineering team.
- Establishes relationships with researchers and groups to provide continued support on disease or domain specific initiatives.
Required Education and Experience
Required Education: Bachelor’s Degree in biological or computational discipline.Preferred Education, Experience & Cert/Lic
Preferred Education: Master’s Degree in biological or computational discipline. Preferred Experience: Previous experience in applied bioinformatics, computational, and genomics/proteomics areas./ Additional Technical Requirements :
- Strong UNIX/LINUX expertise required.
- Experience with at least two of Python, Perl or R strongly preferred.
- Experience with pipeline or workflow development frameworks preferred.
- Familiarity with open source and commercial bioinformatics resources and software preferred.
- Experience with genomic data analysis preferred.
- Knowledge of the working mechanism of microarray, NGS, or other high-throughput technologies and awareness of their strengths and weaknesses, as well as applicability to a specific biological problem is preferred.
- Familiarity with resources of genomic data sets and analysis tools, such as UCSC Genome Browser, Bioconductor, ENCODE, and NCBI databases is preferred.
- Accountability and attention to timelines.
- Excellent organization and communication skills with an emphasis on strong attention to details.
- Ability to work in a team environment.
Requeriments :
Skills :
- Bioinformatics
- Genetics
- genomic
- Lunix/Unix
- Machine Learning
- Microarray
- Next Generation Sequencing
- Programing in Python
- Programming in PERL
- Programming in R
- Statistics
Areas :
Additional Info:
Req ID: 18765 Shift: Days Employment Status: AF - Active - Regular - Full Time All CHOP employees who work in a patient building or who provide patient care are required to receive an annual influenza vaccine unless they are granted a medical or religious exemption. Children's Hospital of Philadelphia is committed to providing a safe and healthy environment for its patients, family members, visitors and employees. In an effort to achieve this goal, employment at Children's Hospital of Philadelphia, other than for positions with regularly scheduled hours in New Jersey, is contingent upon an attestation that the job applicant does not use tobacco products or nicotine in any form and a negative nicotine screen (the latter occurs after a job offer). Children's Hospital of Philadelphia is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability or protected veteran status. VEVRAA Federal Contractor/Seeking priority referrals for protected veterans. Please contact our hiring official with any referrals or questions. CHOP Careers Contact Talent Acquisition 2716 South Street, 6th Floor Philadelphia, PA 19146 Phone: 866-820-9288 Email: TalentAcquisition@email.chop.edu[Click Here to Access the Original Job Post]