Job Description:
We are seeking a bioinformatics investigator to accelerate the development of immuno-oncology therapies. The successful candidate will serve as a biomarker liaison with clinical teams in Translational Clinical Oncology and Oncology Global Development, including the following responsibilities:
Additional Info:
The Next Generation Diagnostics (NGDx) group in NIBR Oncology has the mission of enabling an in-depth understanding of the molecular basis of therapeutic response for individual cancer patients using cutting-edge technologies. The group generates sequencing data from thousands of oncology clinical samples, which are then analyzed with internal bioinformatics pipelines. EEO Statement The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. [Click Here to Access the Original Job Post]
We are seeking a bioinformatics investigator to accelerate the development of immuno-oncology therapies. The successful candidate will serve as a biomarker liaison with clinical teams in Translational Clinical Oncology and Oncology Global Development, including the following responsibilities:
- Collaborate with Precision Medicine Directors on the design and execution of biomarker profiling studies in clinical trials
- Manage the workflow of sample processing and data transfer, in collaboration with project managers and data engineers
- Assess the utility of candidate biomarkers, such as tumor mutation burden, circulating tumor DNA, RNA signatures, TCR clonality, and cytokines
- Develop analytical approaches for innovative technologies, such as single-cell RNA-seq
- Influence departmental leaders on technology development and deployment
- Mentor junior scientists on data analysis and scientific communication
- Ph.D. in bioinformatics, immunology, molecular biology, computer science, statistics, or related field with 3+ years of experience analyzing next-generation sequencing data
- Solid understanding of cancer genetics and immunology
- Demonstrated experience with analytical methods for DNA-seq and RNA-seq data
- Demonstrated statistical and analytical ability with programming expertise in R
- Effective prioritization among multiple projects
- Excellent interpersonal and communication skills; proven ability to work effectively within a team
- The ideal candidate would also have experience with: Linux tools; Python programming; high-performance computing clusters; single-cell RNA-seq
Requeriments :
Skills :
- Biomarker Discovery
- Cancer biology
- DNA sequencing
- Genetics
- HPC
- immunology
- Lunix/Unix
- Next Generation Sequencing
- Programing in Python
- Programming in R
- RNA-seq
- Statistics
Areas :
Additional Info:
The Next Generation Diagnostics (NGDx) group in NIBR Oncology has the mission of enabling an in-depth understanding of the molecular basis of therapeutic response for individual cancer patients using cutting-edge technologies. The group generates sequencing data from thousands of oncology clinical samples, which are then analyzed with internal bioinformatics pipelines. EEO Statement The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. [Click Here to Access the Original Job Post]