Job Description:
We are seeking an independent and motivated researcher for a Postdoctoral Fellowship in Matthew Albert’s laboratory in the Department of Cancer Immunotherapy to study systems immunology with a focus on understanding the variable response to anti-PDL1 treatment. The successful candidate will join a research team that combines cutting-edge biochemistry, transcriptional profiling, cellular immunology and bioinformatics to discover and elucidate mechanisms of immune regulation. Specifically, our data science based research will utilize clinical trial data to dissect somatic mutations in cell death genes as they are perturbed during cancer pathogenesis. Who You Are:
Additional Info:
Selected publications from the Albert lab: Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors. Patin E, Hasan M, Bergstedt J, Rouilly V, Libri V, Urrutia A, Alanio C, Scepanovic P, Hammer C, Jönsson F, Beitz B, Quach H, Lim YW, Hunkapiller J, Zepeda M, Green C, Piasecka B, Leloup C, Rogge L, Huetz F, Peguillet I, Lantz O, Fontes M, Santo JP, Thomas S, Fellay J, Duffy D, Quintana-Murci L, Albert ML; Milieu Intérieur Consortium. Nat Immunol. 2018 Mar;19(3):302-314. doi: 10.1038/s41590-018-0049-7. Epub 2018 Feb 23. Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges. Piasecka B, Duffy D, Urrutia A, Quach H, Patin E, Posseme C, Bergstedt J, Charbit B, Rouilly V, MacPherson CR, Hasan M, Albaud B, Gentien D, Fellay J, Albert ML, Quintana-Murci L; Milieu Intérieur Consortium. Proc Natl Acad Sci U S A. 2018 Jan 16;115(3):E488-E497. doi: 10.1073/pnas.1714765115. Epub 2017 Dec 27. Dying cells actively regulate adaptive immune responses. Yatim N, Cullen S, Albert ML. Nat Rev Immunol. 2017 Apr;17(4):262-275. doi: 10.1038/nri.2017.9. Epub 2017 Mar 13. Review. For more information on the position, please email albertm7@gene.com. For more information about the postdoctoral program at Genentech, please visit: http://www.gene.com/gene/careers/college/postdoctoral[Click Here to Access the Original Job Post]
We are seeking an independent and motivated researcher for a Postdoctoral Fellowship in Matthew Albert’s laboratory in the Department of Cancer Immunotherapy to study systems immunology with a focus on understanding the variable response to anti-PDL1 treatment. The successful candidate will join a research team that combines cutting-edge biochemistry, transcriptional profiling, cellular immunology and bioinformatics to discover and elucidate mechanisms of immune regulation. Specifically, our data science based research will utilize clinical trial data to dissect somatic mutations in cell death genes as they are perturbed during cancer pathogenesis. Who You Are:
- Applicant must have a recent doctoral degree with strong computational biology and statistical expertise.
- The successful applicant will have a demonstrated record of innovative scientific accomplishments as evidenced by at least one first-author paper published or accepted in a top tier journal.
- Relentless drive and creativity to tackle complex biological questions, enthusiasm to collaborate and learn new methods, rigorous scientific aptitude, and strong communication and organization skills are essential qualities.
- An interests in tumor immunology and cell death.
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Additional Info:
Selected publications from the Albert lab: Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors. Patin E, Hasan M, Bergstedt J, Rouilly V, Libri V, Urrutia A, Alanio C, Scepanovic P, Hammer C, Jönsson F, Beitz B, Quach H, Lim YW, Hunkapiller J, Zepeda M, Green C, Piasecka B, Leloup C, Rogge L, Huetz F, Peguillet I, Lantz O, Fontes M, Santo JP, Thomas S, Fellay J, Duffy D, Quintana-Murci L, Albert ML; Milieu Intérieur Consortium. Nat Immunol. 2018 Mar;19(3):302-314. doi: 10.1038/s41590-018-0049-7. Epub 2018 Feb 23. Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges. Piasecka B, Duffy D, Urrutia A, Quach H, Patin E, Posseme C, Bergstedt J, Charbit B, Rouilly V, MacPherson CR, Hasan M, Albaud B, Gentien D, Fellay J, Albert ML, Quintana-Murci L; Milieu Intérieur Consortium. Proc Natl Acad Sci U S A. 2018 Jan 16;115(3):E488-E497. doi: 10.1073/pnas.1714765115. Epub 2017 Dec 27. Dying cells actively regulate adaptive immune responses. Yatim N, Cullen S, Albert ML. Nat Rev Immunol. 2017 Apr;17(4):262-275. doi: 10.1038/nri.2017.9. Epub 2017 Mar 13. Review. For more information on the position, please email albertm7@gene.com. For more information about the postdoctoral program at Genentech, please visit: http://www.gene.com/gene/careers/college/postdoctoral[Click Here to Access the Original Job Post]