RESEARCH ASSOCIATE – Computational modeling of immune system

Job ID: 91503
Job date: 2017-04-18
End Date:

Company : Cincinnati Children's Hospital Medical Center 

Country :

Role : Research Scientist 


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Job Description:
PURPOSE OF POSITION: To conduct independent research and support the independent research of others in a Medical Center dedicated to the care of infants, children, and adolescents.

We seek a computational biologist for a collaborative research position in theDivisions of Immunobiology and Biomedical Informatics. The candidate will bring bioinformatics andcomputational modeling expertise to multi-disciplinary, team-based projects (includingcomputational biologists, experimentalists, mathematicians, clinicians,computer scientists). Many of theprojects will involve mathematical modeling of the immune system fromhigh-dimensional genomics measurements in systems biology studies. The candidate will also have the opportunityto contribute to broader endeavors in Biomedical Informatics, includingprecision medicine, computational infrastructure, and data-mining.

MAJOR DUTIES AND RESPONSIBILITIES:

Perform analysis and experiments: Design, execute, and record analysis and experiments; apply standard scientific protocols to research, and improve current methods and evaluate innovative techniques. Develop and implement human subject research protocols, vertebrate animal research protocols and design experimental procedures and documentation in accordance with the relevant laws and regulations. Prepare, clean and analyze data. Maintain optimal protocol and accuracy by conducting regular quality and reproducibility checks.

Communicate results/findings: Draft, write, and edit scientific reports, papers, journal articles, and abstracts. Present information on research and department work to others at department meetings, journal clubs, and seminars. Present results and discuss relevant insights with Faculty and provide useful recommendations and analysis.

Innovate and advance departmental capabilities: Independently reproduce, evaluate, research, and improve techniques currently used. Adapt new methods to existing procedures and modify current analysis/experiments through scientific knowledge and intuition. Maintain accurate and detailed records of all analysis and experiments. Develop, set-up, and verify new procedures in the department. Standardize and establish new published procedures; evaluate innovative techniques. Develop new protocols; design formats. Maintain an integral role in the department's meetings, presentations, and publications. Troubleshoot and correct erroneous results or problems with department software/equipment. Maintain and repair software/equipment; monitor proper use by personnel.

Financial/Budgeting: Assist in preparing grant applications. Assist in preparing, writing, and maintaining fiscal budget. Monitor expenditures and prepare capital expenditure requests. Prepare, approve, and initiate check requests; track funding, maintain accurate balance, and resolve any discrepancies.

Staff Leadership: May provide day-to-day functional leadership for a team or directly manage a minimal number of support staff. Establishes team goals. Gives input into, and performs employee performance reviews. Oversees and guides work assignments. Serves as the functional expert and provides guidance to the team.

Education and Training: May serve as course master and develop new courses at the undergraduate and graduate level, including appropriate plans for evaluating student performance; may deliver lectures as a guest lecturer in courses organized by other faculty. Assist in the training of new employees. Serve as a resource and/or mentor to coworkers. Assist in the development and presentation of department training. Identify training needs and provide necessary coaching.

EDUCATION\WORK EXPERIENCE:

Required:

•Ph.D., MD, or equivalent degree

•Three years' related experience.

Preferred:

•PhD in Computer Science, Physics, Biomedical Informatics, Bioinformatics, other similar quantitative disciplines.

•The candidate will have significant computational biology and bioinformatics background as well as a solid background in computer science fundamentals (algorithms, data structures, runtime analysis, etc.) to tackle a number of challenges arising from building models from genomics datasets. To this end, the challenges of the position include:

•managing and manipulating hundreds to thousands of muti-gigabyte data files oefficient processing over large datasets is a must.

•designing workflows incorporating external tools and modules (compiled and/or interpreted, written in a variety of languages) to process and transform data .

•efficiently mapping these workflows to a computing cluster.

•interacting with non-computational scientists and analysts to bridge the theory/practice gap.

•communicating technical matters clearly and concisely within the lab and to the larger community via contributions to documentation and publications.

REQUIRED SKILLS:

Organization: Possess strong organization skills and attention to detail

Research Methods Skills: Designing and conducting effective research studies that address measurement, data collection, and validity issues; identifying or developing appropriate, accurate, relevant, and reliable measurement methods; drawing appropriate conclusions from study results.

Analysis: Strong analytical skills with the ability to make judgments and recommendations based on statistical analysis.

Statistics - Intermediate: Familiarity with statistical software, statistical techniques, statistical process control principles, and graphical data display.

Information Analysis:

Time Management: Prioritization and time-management skills sufficient to meet deadlines in a fast-paced environment

Communication – Advanced: Excellent verbal, written and/or interpersonal communication skills

Programming – Basic: Working knowledge of programming

Writing – Scientific: Strong scientific writing abilities


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Additional Info:
Cincinnati Children’s is an Equal Opportunity Employer. Qualified applicants receive consideration for employment without regard to race, color, religion, sex, national origin, age, genetic information, physical or mental disability, military or veteran status, sexual orientation, gender identity/expression, or other protected status in accordance with applicable federal, state, and local laws and regulations.

Cincinnati Children’s will not discriminate against applicants and employee for inquiring about, discussing or disclosing their pay or, in certain circumstances, the pay of their co-workers.

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