Job ID: 589793124
Job date: 2018-03-22
End Date:
Company : A*STAR - Agency for Science Country : Role : Research Scientist
Job date: 2018-03-22
End Date:
Company : A*STAR - Agency for Science Country : Role : Research Scientist
Job Description:
The Singapore Institute for Clinical Sciences (SICS), Agency of Science and Technology Research (A*STAR) is seeking to appoint an outstanding post-doctoral Bioinformatician in the Systems Biology group. The Systems Biology group focuses on in-depth genomic and epigenomic analysis of highly prevalent metabolic and developmental diseases (e.g. diabetes, obesity and neurodevelopment) for biomarker discovery. The candidate should be highly motivated and have an expertise in Next-Generation Sequencing (NGS) data analysis (such as RNA-seq). The successful candidate will be involved in analyzing genomic data generated from valuable samples obtained from birth cohorts and other trials. S/he will be part of collaborations with biological discovery groups, clinicians, pharmaceuticals and nutritional agencies. Job Responsibilities:
Additional Info:
Company Profile: The Agency for Science, Technology and Research (A*STAR) is Singapore’s lead government agency for economic-oriented Research and Development (R&D). We advance science and develop innovative technology to further economic growth and improve lives. For more information about A*STAR, please visit: www.a-star.edu.sg DIVISION & RI / ENTITY PROFILE About the Agency for Science, Technology and Research (A*STAR) The Agency for Science, Technology and Research (A*STAR) is Singapore's lead public sector agency that fosters world-class scientific research and talent to drive economic growth and transform Singapore into a vibrant knowledge-based and innovation driven economy. About Singapore Institute For Clinical Sciences (SICS) Established in 2007, the Singapore Institute for Clinical Sciences (SICS) is a research institute within the Agency for Science, Technology and Research (A*STAR), and its mission is to develop clinical and translational research programmes in key disease areas. SICS is distinguished by its focus on clinical sciences and the use of innovative approaches and technologies that enable the efficient and effective study of human health and diseases. The clinical scientists in SICS conduct the full spectrum of “bench to bedside” research activities in metabolic diseases (including diabetes, obesity and insulin resistance), pathways to normal growth and development (including cognitive and behavioural development), and nutritional sciences. The institute aims to attract, train and nurture clinician-scientists and to develop joint programmes with universities, academic medical centres, government hospitals and research institutes. For more information about A*STAR and SICS, please visit www.a-star.edu.sg and www.sics.a-star.edu.sg respectively. About the Agency for Science, Technology and Research (A*STAR) The Agency for Science, Technology and Research (A*STAR) is Singapore's lead public sector agency that spearheads economic oriented research to advance scientific discovery and develop innovative technology. Through open innovation, we collaborate with our partners in both the public and private sectors to benefit society. As a Science and Technology Organisation, A*STAR bridges the gap between academia and industry. Our research creates economic growth and jobs for Singapore, and enhances lives by contributing to societal benefits such as improving outcomes in healthcare, urban living, and sustainability. We play a key role in nurturing and developing a diversity of talent and leaders in our Agency and Research Institutes, the wider research community and industry. A*STAR oversees 18 biomedical sciences and physical sciences and engineering research entities primarily located in Biopolis and Fusionopolis. For more information on A*STAR, please visit www.a-star.edu.sg.[Click Here to Access the Original Job Post]
The Singapore Institute for Clinical Sciences (SICS), Agency of Science and Technology Research (A*STAR) is seeking to appoint an outstanding post-doctoral Bioinformatician in the Systems Biology group. The Systems Biology group focuses on in-depth genomic and epigenomic analysis of highly prevalent metabolic and developmental diseases (e.g. diabetes, obesity and neurodevelopment) for biomarker discovery. The candidate should be highly motivated and have an expertise in Next-Generation Sequencing (NGS) data analysis (such as RNA-seq). The successful candidate will be involved in analyzing genomic data generated from valuable samples obtained from birth cohorts and other trials. S/he will be part of collaborations with biological discovery groups, clinicians, pharmaceuticals and nutritional agencies. Job Responsibilities:
- Bioinformatics analyses of NGS data (eg. RNA-seq)
- Preparation of scientific publications, data reports and presentations
- To maintain good documentation of analysis pipeline in keeping with good scientific practices
- To act as the provider of skilled training in the area of bioinformatics data analysis to other members in the team
- Familiarity with widely used genomic databases and software.
- Willingness to assess and adapt to new tools and methodologies.
- Ph . D . degree in Statistics, Computational Biolog y , Bioinforma t i c s or equivalent qualification
- Proven productivity by previous publications in peer-reviewed biology journals is essential.
- Proven experience of deploying NGS toolkits for genomic data analysis, integration and visualization
- R programming and Bioconductor packages
- Basic Unix shell scripting
- High performance computing experience
- Git, markdown, etc
- Aptitude for and experience of collaborative research
- Capable of multitasking and meeting deadlines
- Highly developed critical thinking and troubleshooting skills
- Good interpersonal and communication skills
- Highly self-motivated with excellent communication and writing skills in English language.
- Strong desire to learn in a dynamic multi-disciplinary research environment.
- Experience with small RNA, circular RNA or lncRNA data analysis
- A strong background in statistics and quantitative data analysis
- Experience with microarray data analysis, limma, WGCNA, GSEA
- Experience with eQTLs/meQTLs, to identify allele-specific effects
- Ability to work independently and goal oriented to meet multiple priorities
- Experience of working in a biotechnology industry, team with collaborators or a consortium
Requeriments :
Skills :
- genomic
- HPC
- Lunix/Unix
- Microarray
- Next Generation Sequencing
- Programming in R
- RNA-seq
- Shell scripting
- Statistics
Areas :
Additional Info:
Company Profile: The Agency for Science, Technology and Research (A*STAR) is Singapore’s lead government agency for economic-oriented Research and Development (R&D). We advance science and develop innovative technology to further economic growth and improve lives. For more information about A*STAR, please visit: www.a-star.edu.sg DIVISION & RI / ENTITY PROFILE About the Agency for Science, Technology and Research (A*STAR) The Agency for Science, Technology and Research (A*STAR) is Singapore's lead public sector agency that fosters world-class scientific research and talent to drive economic growth and transform Singapore into a vibrant knowledge-based and innovation driven economy. About Singapore Institute For Clinical Sciences (SICS) Established in 2007, the Singapore Institute for Clinical Sciences (SICS) is a research institute within the Agency for Science, Technology and Research (A*STAR), and its mission is to develop clinical and translational research programmes in key disease areas. SICS is distinguished by its focus on clinical sciences and the use of innovative approaches and technologies that enable the efficient and effective study of human health and diseases. The clinical scientists in SICS conduct the full spectrum of “bench to bedside” research activities in metabolic diseases (including diabetes, obesity and insulin resistance), pathways to normal growth and development (including cognitive and behavioural development), and nutritional sciences. The institute aims to attract, train and nurture clinician-scientists and to develop joint programmes with universities, academic medical centres, government hospitals and research institutes. For more information about A*STAR and SICS, please visit www.a-star.edu.sg and www.sics.a-star.edu.sg respectively. About the Agency for Science, Technology and Research (A*STAR) The Agency for Science, Technology and Research (A*STAR) is Singapore's lead public sector agency that spearheads economic oriented research to advance scientific discovery and develop innovative technology. Through open innovation, we collaborate with our partners in both the public and private sectors to benefit society. As a Science and Technology Organisation, A*STAR bridges the gap between academia and industry. Our research creates economic growth and jobs for Singapore, and enhances lives by contributing to societal benefits such as improving outcomes in healthcare, urban living, and sustainability. We play a key role in nurturing and developing a diversity of talent and leaders in our Agency and Research Institutes, the wider research community and industry. A*STAR oversees 18 biomedical sciences and physical sciences and engineering research entities primarily located in Biopolis and Fusionopolis. For more information on A*STAR, please visit www.a-star.edu.sg.[Click Here to Access the Original Job Post]