Job ID:
Job date: 2018-03-03
End Date:
Company : Clarivate Analytics Country : Role : Research Scientist
Job date: 2018-03-03
End Date:
Company : Clarivate Analytics Country : Role : Research Scientist
Job Description:
Clarivate Analytics clients are the trailblazers and risk takers who come up with life-changing ideas. We’re looking for our own trailblazers to help us keep providing clients some of the world’s most trusted brands, spanning scientific and academic research, patent analytics, pharmaceutical and biotech intelligence and IP management. We’re an independent owned company with a rich heritage and a bold entrepreneurial mission. If you’re excited by the thought of helping people and organizations go from new ideas to life-changing innovations faster, we’re excited to consider you for a position at Clarivate. Clarivate Analytics (US) LLC / Senior Research Scientist : 1. Responsible for the delivery and scientific strategy of bioinformatics projects related to molecular biology, disease biology, drug development and related disciplines; 2. Provide bioinformatics consultations to clients, recommend technology-based solutions and determine computational strategies based on the clients’ large molecular datasets and research needs; 3. Communicate research results through bioinformatics project reports, including introduction, results, discussion, conclusions and recommendations for further research; communicate results through scientific publications; 4. Analyze genomic, gene expression, proteomic, metabolomic and other large molecular datasets using biostatistics and bioinformatics techniques and knowledge on pathways and processes involved in cancer and other diseases: apoptosis, cell cycle, metabolism, inflammation, adhesion, and others; 5. Develop new software applications and customize existing algorithms to specific scientific project needs; 6. Manage scientific collaborations with research institutions in the field of drug target identification and repositioning, with a focus in immunology and oncology areas; 7. Identify drug targets using molecular network algorithms based on information from publicly accessible and proprietary databases and its integration using machine learning techniques; create target dossiers for already known targets; 8. Design and apply algorithms to perform drug repositioning analyses using cheminformatics, bioinformatics and literature mining approaches; 9. Identify molecular biomarkers (e.g. mutations, gene expression, and others) for cancer and other diseases using bioinformatics analysis of large molecular datasets. Position Requirements: Ph.D in Bioinformatics, Biochemistry, Chemistry, Photochemical Sciences or a related discipline followed by three years of experience in bioinformatics or computational biology in a biotechnology, pharmaceutical, or consulting setting. Experience must include the following, which may be gained concurrently: 1) 2 years of experience in statistical programming languages (including R), scripting languages (including Perl and Python) and database query languages (including SQL); 2) 2 years of experience in functional analysis and biomarker identification from microarray data (including identification of differentially expressed genes, enrichment analysis, WGCNA, GSEA, clustering); 3) 2 years of machine learning analysis of high-dimensional data (including PLS, random forests, elastic net, and neural networks); 4) 2 years of experience in cheminformatics including metabolic rules, QSAR models, in silico toxicology/DMPK, docking, and structure analysis (including Swiss PDB viewer and Swiss-Model); 5) 2 years of experience working with clinical trial data and clinical ontologies; 6) 2 years of experience in target identification and repositioning using molecular network algorithms (including overconnectivity, causal reasoning, and network propagation); 7) 2 years of experience in cancer biology and inflammation and immunology therapeutic areas; 8) 2 years of experience with scientific workflow systems (including KNIME and Pipeline Pilot); 9) 2 years of experience with OMICs data warehouses (including tranSMART).
Additional Info:
Job site: 30 Thomson Pl, Boston, MA 02210. Full-time. JOB OPPORTUNITY QUALIFIES FOR EMPLOYEE INCENTIVE REFERRAL PROGRAM. To learn more & to apply online, visit our website at: https://clarivate.com/careers & reference Req. # JREQ101479.[Click Here to Access the Original Job Post]
Clarivate Analytics clients are the trailblazers and risk takers who come up with life-changing ideas. We’re looking for our own trailblazers to help us keep providing clients some of the world’s most trusted brands, spanning scientific and academic research, patent analytics, pharmaceutical and biotech intelligence and IP management. We’re an independent owned company with a rich heritage and a bold entrepreneurial mission. If you’re excited by the thought of helping people and organizations go from new ideas to life-changing innovations faster, we’re excited to consider you for a position at Clarivate. Clarivate Analytics (US) LLC / Senior Research Scientist : 1. Responsible for the delivery and scientific strategy of bioinformatics projects related to molecular biology, disease biology, drug development and related disciplines; 2. Provide bioinformatics consultations to clients, recommend technology-based solutions and determine computational strategies based on the clients’ large molecular datasets and research needs; 3. Communicate research results through bioinformatics project reports, including introduction, results, discussion, conclusions and recommendations for further research; communicate results through scientific publications; 4. Analyze genomic, gene expression, proteomic, metabolomic and other large molecular datasets using biostatistics and bioinformatics techniques and knowledge on pathways and processes involved in cancer and other diseases: apoptosis, cell cycle, metabolism, inflammation, adhesion, and others; 5. Develop new software applications and customize existing algorithms to specific scientific project needs; 6. Manage scientific collaborations with research institutions in the field of drug target identification and repositioning, with a focus in immunology and oncology areas; 7. Identify drug targets using molecular network algorithms based on information from publicly accessible and proprietary databases and its integration using machine learning techniques; create target dossiers for already known targets; 8. Design and apply algorithms to perform drug repositioning analyses using cheminformatics, bioinformatics and literature mining approaches; 9. Identify molecular biomarkers (e.g. mutations, gene expression, and others) for cancer and other diseases using bioinformatics analysis of large molecular datasets. Position Requirements: Ph.D in Bioinformatics, Biochemistry, Chemistry, Photochemical Sciences or a related discipline followed by three years of experience in bioinformatics or computational biology in a biotechnology, pharmaceutical, or consulting setting. Experience must include the following, which may be gained concurrently: 1) 2 years of experience in statistical programming languages (including R), scripting languages (including Perl and Python) and database query languages (including SQL); 2) 2 years of experience in functional analysis and biomarker identification from microarray data (including identification of differentially expressed genes, enrichment analysis, WGCNA, GSEA, clustering); 3) 2 years of machine learning analysis of high-dimensional data (including PLS, random forests, elastic net, and neural networks); 4) 2 years of experience in cheminformatics including metabolic rules, QSAR models, in silico toxicology/DMPK, docking, and structure analysis (including Swiss PDB viewer and Swiss-Model); 5) 2 years of experience working with clinical trial data and clinical ontologies; 6) 2 years of experience in target identification and repositioning using molecular network algorithms (including overconnectivity, causal reasoning, and network propagation); 7) 2 years of experience in cancer biology and inflammation and immunology therapeutic areas; 8) 2 years of experience with scientific workflow systems (including KNIME and Pipeline Pilot); 9) 2 years of experience with OMICs data warehouses (including tranSMART).
Requeriments :
Skills :
- Bioinformatics
- Biostatistics
- Cancer biology
- genomic
- immunology
- Machine Learning
- molecular biology
- Programing in Python
- Programing Skills
- Programming in PERL
- Programming in R
- SQL
- Statistics
Areas :
Additional Info:
Job site: 30 Thomson Pl, Boston, MA 02210. Full-time. JOB OPPORTUNITY QUALIFIES FOR EMPLOYEE INCENTIVE REFERRAL PROGRAM. To learn more & to apply online, visit our website at: https://clarivate.com/careers & reference Req. # JREQ101479.[Click Here to Access the Original Job Post]