Job Role: Postdoc

Postdoctoral Research Scientist – Molecular Pathology The Gynaecological Oncology Research Group within the Centre for Cancer Research aims to better target treatment to individual patients through understanding the molecular drivers of treatment response in ovarian cancer. With researchers forming an integral part of the multidisciplinary team caring for women with gynaecological cancers at Westmead Hospital, research conducted by the group is well-positioned to be quickly translated into new tests and treatments that are of direct benefit to patients. The group is seeking a Postdoctoral Research Scientist in the field of Molecular Pathology to provide molecular and genomic expertise to a new Translational Research Program. The position will be part of a collaborative team working to integrate genomic pathology into the multidisciplinary team based model of care for ovarian cancer. This is a full-time position on a 3 year contract. Major Responsibilities: Developing clinical quality accredited molecular assays. Mutation variant reporting and analysis of other somatic alterations that contribute to ovarian cancer pathogenesis and response to treatment, including gene copy number and gene expression variations, within a team environment. Integration of analysis methods and interpretation of data from a range of molecular assay platforms. Implementation of bioinformatics pipelines for the analysis of molecular data. Working with collaborators within the Institute of Clinical Pathology and Medical Research and Pathology West to implement new molecular assays into routine clinical practice within the health care system. Contribute to the research activities of the Gynaecological Oncology Research Group as directed by the Head. Collect and coordinate data requirements for research projects, grant applications and publications as directed by the Head of the Gynaecological Oncology Research Group. Closing Date: 7th July 2016 To submit your application please click on the  [More]

Uppsala universitet: The Department of Cell and Molecular Biology is one of the most international, broad and distinguished biomolecular departments in Europe, comprising six research programs covering subjects such as bioinformatics, microbiology and biophysics. The cand Sweden  [More]

International Institute of Molecular and Cell Biology: Two PhD student position in RNA bioinformatics are available in the Bujnicki group in IIMCB, Warsaw, Poland. We are looking for junior scientist with energy and passion, interested in bioinformatics, software development and biological data analysis, an Poland  [More]

We are seeking individuals with exceptional scientific credentials to join a vibrant, dynamic team at CSISingapore. Several full-time postdoctoral positions* are immediately available for MD and/or Ph.D graduates in the various labs: Prof Daniel Tenen Research Area: (i) Bioinformatics (ii) Molecular/cell biology A/Prof Henry Yang Research Area: Bioinformatics and Database A/Prof Richie Soong Research Area: Medical genomics Dr Yvonne Tay Research Area: Regulatory RNA networks Dr Melissa Fullwood Research Area: (i) Bioinformatics (ii) Genomics Dr Takaomi Sanda Research Area: Novel therapeutic targets in T-cell leukemia Dr Touati Benoukraf Research Area: Molecular Biology Please use the  [More]

Postdoctoral Scientist – Bioinformatics MRC Toxicology Unit, Leicester Fixed Term for 5 years Salary £28,935 - £32,648 The Medical Research Council Toxicology Unit, (currently located at the University of Leicester but relocating to the University of Cambridge in 2018), is an internationally renowned institution focussed on the delivery of field-changing mechanistic insights into toxicology and disease.  We are equipped with state-of-the-art facilities and provide a supportive and learning environment helping postdoctoral scientists to establish themselves as successful research scientists in their chosen field.  Applications are invited for a postdoctoral scientist/bioinformatician to carry out detailed bioinformatics analysis on large data sets generated from proteomic and transcriptomic studies on localised RNA binding proteins. You will join the post transcriptional control group, led by Professor Anne Willis to work on a project funded by a joint Wellcome Trust Investigator award to Professor Anne Willis and Professor Kathryn Lilley University of Cambridge.  The project is entitled “Transcription, Trafficking, Translation: dissecting the spatiotemporal mechanisms underlying localised protein synthesis”. It is now widely acknowledged that mRNA is spatially organised such that its translation frequently occurs in the vicinity where the corresponding protein product adopts its function.  This phenomenon has been studied extensively in specialised cells, however, recent research has suggested that spatial restriction of mRNA storage and translation is much more widespread. The aims of this project are to define where translation of mRNA takes place in the cell, how this is regulated by protein binding partners and sequence motifs and how this changes upon cellular perturbation. For more information please visit: http://tox.mrc.ac.uk/research/willis-group/  [More]

Postdoctoral Fellow - Senior Bioinformatician Salary range: £30655 to £38428pa plus excellent benefits Fixed-term for 3 years We are looking for a creative, motivated and collaborative bioinformatician/postdoctoral scientist to join the Host-Microbiota Interactions Laboratory (www.lawleylab.com) investigating interactions between host and microbiota during health and disease.  The group has projects focused on infectious diseases, antibiotic therapies, autoimmune diseases and early life colonization. The lab is very collaborative and consists of microbiologists, bioinformaticians, cell biologists and mouse biologists so there is ample capacity for the individual to develop new skill sets. The group is well resourced giving the individual access to cutting edge genomic and proteomic tools (host and microbiota), human organoids, transgenic mice, germ free mice, a human microbiota bacterial culture collection and state of the art anaerobic culturing facility. The lab is focused on translational science with links to the biotech industry. The Lawley Lab has developed unique capabilities to culture the majority of bacteria in the human intestinal microbiota (Browne et al. 2016. Nature). The Lab maintains an extensive bacterial culture collection of >300 species and has sequenced all species to generate reference genome database (Forster et al. 2016. NAR). The individual will use advanced genomic analysis methods and generally focus on establishing the phylogenies and accessory genomes of dominant bacterial clades the human intestinal microbiota to assist in identifying functional attributes of bacteria that promote health. This is a unique position as the project leverages a comprehensive human microbiota culture collection and associated genomic data combined with cutting edge laboratory culturing and animal model facilities in a world leading genome research institute. The applicant should have a strong background in bioinformatics, a knowledge of microbiology and have an interest in learning about host-pathogen interactions and the biology of host-associated microbial communities during health and disease. Key Responsibilities include: Manage and analyse large-scale whole-genome sequencing datasets and their associated projects Perform analysis on datasets generated by next generation sequencing platforms Integrate sequence data with biological experiments/phenotypic data Liaise with collaborators and coordinate projects Train group members Develop software and develop new methods to analyse sequence data  [More]

PostDoc/Scientist: Epigenomics and Transcriptomics of Human Diseases Themes: Epigenomics (special focus on underexplored and new types of epigenetic variations), Transcriptomics, Integrate Single Molecule Sequencing (PacBio, Oxford Nanopore) + Illumina, Systems Biology of Human Diseases Job description and Our Unique Expertise: Postdoc fellow and Senior Scientist positions at the Mount Sinai School of Medicine (Top-20 medical school in the US) in New York City. Our lab is in the Department of Genetics and Genomic Sciences and the Institute for Genomics and Multi-scale Biology. Our lab (80% computation + 20% experimental) pioneered the fast growing field of bacterial epigenomics with different forms of DNA methylations (e.g. 6mA, 4mC) beyond 5mC (the one extensively studied in human). Recent work by us and others discovered that not only does 6mA exists in eukaryotes including human, but it also has significant functional roles. A major focus of our lab is to explore this young and promising field of 6mA epigenomes, discover other novel types of DNA modifications, their relationship to well-studied DNA/histone modifications, and make fundamentally new discoveries about human diseases: infectious diseases, cancers and mental disorders. We have unique expertise in the use of third generation sequencing (single molecule real-time, ~20kbp read length, and the emerging nanopore technique) with advantages of detecting different types of DNA modifications, single molecule-level epigenetic phasing, full-length transcript isoforms, complex structural variations. Successful candidates will have unique opportunities to i) build on our unique expertise, large scale collection of clinically relevant samples and a strong network of collaborators, ii) take the lead role in multiple projects on the innovative use of third-generation sequencing and systems biology to pioneer the mapping and characterization of novel forms of DNA methylations in eukaryotic genomes for both basic biology and clinical applications. Compensations for successful candidates are highly competitive. Subsidized housing (in New York City) is also available. Recent publications: * Cell Reports, 2016 * Nature, 2016 * Nature Communications, 2015 * PLoS Genetics, 2015 * Biological Psychiatry, 2015 * Nature Communications, 2014 * Molecular Psychiatry, 2014 * PLoS Genetics, 2013 * PLoS Computational Biology, 2013 * Nature Biotechnology, 2012 * Genome Research, 2012  [More]

The Center for Systems Biology Dresden calls for applications for several open postdoc positions in within the prestigious ELBE Postdoctoral Fellowship Program in the following areas Computer Science, Computational Science and Applied Mathematics Bioinformatics and Computational Biology Biological Physics, Biophysics and Theoretical Biology We seek outstanding candidates with a degree in the listed areas and a strong interest in working in a multi-disciplinary environment towards developing and using computational and physical methods to address key questions in biology and to transform data into knowledge. The Center for Systems Biology Dresden is a joint activity by the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG) and the Max Planck Institute of the Physics of Complex Systems (MPI-PKS). The center is a highly interactive and collaborative workplace with an international atmosphere where English is the working language, and has a strong commitment to interdisciplinary training and career development. The center provides access to cutting-edge computer infrastructure, genome sequencing technology and wet lab facilities. The MPI-CBG has been awarded one of the “Best Places To Work for Postdocs” in 2011. ELBE Fellowships are awarded on a competitive basis to outstanding young researchers with a doctoral degree. To foster collaboration, fellows are usually affiliated with two hosting groups working in different disciplines.  [More]

2016/17 PhD program at IMT School for Advanced Studies Lucca Applications are now being accepted for scholarships for the Computer Science and Systems Engineering (CSSE) curriculum within the 2016/17 PhD program at the IMT School for Advanced Studies Lucca (www.imtlucca.it), one of the five Schools of Excellence in Italy. Perspective students should preferably have a master-level background in computer science, engineering, physics, mathematics, statistics, or in a related field. The CSSE curriculum provides the doctoral student with a solid interdisciplinary background to analyze cyber-physical systems and provide solutions to a huge variety of complex engineering problems. The program of studies is based on a set of common courses, covering the fundamentals of numerical linear algebra and numerical methods for differential equations, computer programming, dynamical systems and control, numerical optimization, stochastic processes, and machine learning. These basic courses are followed by a number of advanced courses and research seminars related to the different areas of specialization for the PhD work that can be chosen by the student: research in computer science, carried out within the SysMA unit, deals with the development of languages and techniques for the analysis and verification of modern concurrent and distributed systems. Specific areas of expertise are concurrency theory, programming languages, and software engineering, with a wide range of applications such as adaptive systems, cyber-physical systems, cloud computing, computational biology, fault-tolerant systems, security, and transportation networks;  research in control systems, carried out within the DYSCO unit, is oriented towards optimization algorithms for model predictive control and systems identification of dynamical systems and for machine learning, with an emphasis on real-time embedded optimization algorithms and on their application in industrial problems arising from the automotive, aerospace, and smart-grid domains; research in computational mechanics, carried out within the MUSAM unit, is concerned with the development of innovative computational methods to study advanced problems of solid mechanics, fluid mechanics, and cutting-edge problems involving multiple fields and length scales of high interest in both the academic and industrial sectors. Courses are led by world-renowned academics and provide students with all the theoretical skills and advanced tools required for rigorously tackling a multitude of analysis and design problems. Faculty members and researchers create a network that provides close guidance and support throughout the PhD Program, enabling students to reach the highest levels of scholarly achievement. PhD graduates will be able to use the skills they acquired during their studies to recognize and resolve complex problems in a broad area of application domains and across computer science, systems engineering, and applied mathematics. All students are based in the recently restored San Francesco complex, a fully integrated Campus in the historical center of the beautiful Tuscan city of Lucca. The Campus includes renewed residential facilities, an on-site canteen, study and living rooms, a state-of-the-art library and outdoor recreational spaces, which foster a unique cultural, professional and social environment for our doctoral program. Eligible students, in addition to free room and board, will also receive a research scholarship which amounts to approximately €13,600/year. Additional funding for research stages also will be provided. The PhD program at the IMT School attracts students from around the world, providing a truly international environment. English is the official language of the School. Moreover, all students will have the opportunity to spend periods abroad at research institutes, laboratories or universities, both within the Erasmus+ framework and through ad hoc mobility agreements. Most IMT School PhD Graduates have reached prominent roles in academics, governmental institutions, public and private companies or professions across the globe.   For further information and to apply for this job, please click on the  [More]

Job ID: 28100 Date Posted: 05/24/2016 Location: Center for Life Sciences Job Family: Research - Laboratory Full/Part Time: Full-Time Regular/Temporary: Regular FLSA Status: Exempt About Dana-Farber Located in Boston, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. Overview Join Chris Sander's group as a postdoc at Dana-Farber Cancer Institute (cBio Center at DFCI) or Harvard Medical School (computational biology collaboratory at HMS), with links to the Broad Institute. We are forming a dynamic group of smart scientists to make scientific discoveries in basic biology and help cure cancer. On computers, in the lab and in collaboration with clinicians. Work with us on: Perturbation biology and network pharmacology Cancer genomics and proteomics and metabolomics Protein structure, function & evolution Biological information resources Join a highly interactive team of postdocs, graduate students and software engineers. Work on algorithms and computational analysis, and/or on combination therapy and evolution experiments in the wet lab. Collaborate with others and lead a project. Check your predictions against experiment. Do imaginative basic science and help apply it in real life. You have a PhD or equivalent in biology, medicine, mathematics, computer science, physics, chemistry or engineering. Your appointment will be in the Department of Biostatistics and Computational Biology at DFCI or the Department of Cell Biology at HMS. Send CV, bibliography, brief statement of research interests and names of 3 references to cbio.jobs{at}jimmy.harvard.edu. Then pack your bags and spend a few years doing productive research in computational and systems biology in the silicon valley of the life sciences: Boston, Massachusetts. Science for peace and research for a better quality of life. The mission of Dana-Farber Cancer Institute is to provide expert, compassionate care to children and adults with cancer while advancing the understanding, diagnosis, treatment, cure, and prevention of cancer and related diseases. Our Core Values are: Impact - Above all else, we make a difference by relieving the burden of disease now and for the future through our research, clinical care, education, outreach and advocacy. Excellence - We pursue excellence relentlessly and with integrity in all that we do, adhering always to the highest standards of conduct. Compassion and respect - For those in our care and for one another. Discovery - We foster the spirit of inquiry, promoting collaboration and innovation across traditional boundaries while celebrating individual creativity. Schedule Standard Hours: Monday - Friday How to Apply Please apply directly online at http://www.dana-farber.org/Careers/Careers-at-Dana-Farber.aspx. Click Search Job Openings and use the Job ID number to quickly locate the appropriate job listing. Once you have located the desired job, click on the checkbox in the 'Select' column, and then click the 'Apply Now' button, located at the bottom of the screen. DFCI Employees please apply directly through PeopleSoft Self Service. Sign on to PeopleSoft and navigate to Main Menu > DFCI Careers. Equal Employment Opportunity Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.     Apply Here: http://www.Click2Apply.net/3vydp33bxj  [More]