Job Role: Postdoc
Careers Start Here. A highly motivated post-doctoral research fellow is sought to carry out a research project in the lab of Dr. Andrew Hsieh at Fred Hutchinson Cancer Research Center in Seattle, WA. Applicants should be interested in the application of basic science and RNA biology research towards clinically intractable problems faced by cancer patients and will be expected to be scientifically intrepid. About the Hsieh Lab The primary focus of the Hsieh lab (http://research.fhcrc.org/hsieh/en.html) is to unravel the post-transcriptional mechanisms that govern the genesis and progression of epithelial malignancies. Our research seeks to understand how rogue cells co-opt the critical structure-function relationship between RNA and the protein synthesis machinery to drive specific cancer behavior at a molecular, cellular, and organismal level (Hsieh et al. Cancer Cell 2010, Hsieh et al. Nature 2012, Hsieh et al. Science Signaling 2015). We achieve this through utilizing cutting sequencing techniques and novel primary cell and animal models. Ultimately, we aim to utilize our fundamental discoveries in transnational control biology to tackle critical issues faced by cancer patients today. To be considered, candidates must have: A recent PhD, MD/PhD, or MD in a relevant biological field A strong background in RNA biology Experience with molecular and cellular biology techniques A demonstrated track record of productive research, with at least one first author paper Experience with bioinformatics is highly desirable An ability to work both independently and as part of a laboratory team Pay, Benefits, & Work Schedule: Full time position Salary DOE + excellent benefits To Apply: Please apply with a letter summarizing previous work experience, future research interests, and contact information for three professional references. If interested, please apply online via the [More]
Recognized as a world leader of genomic research in pediatric cancer, the Computational Biology department at St. Jude Children’s Research Hospital (SJCRH) is currently seeking exceptional and creative scientists for multiple POSTDOCTORAL RESEARCH ASSOCIATE positions in the lab of Dr. Jinghui Zhang (www.stjude.org/zhang) to develop and apply innovative analytical and visualization approaches for studying the genome and epigenome of pediatric cancer. The fellows will have access to a wealth of resources including high-quality data, a state-of-art high-performance computing facility, robust analytical pipelines, the latest laboratory technology and research expertise in genomics, cancer biology, mathematics and computer science. The fellows will lead or participate in all aspects of cancer omics studies via multi-disciplinary teamwork and have opportunities to interact with leaders of pediatric cancer and translational research within and outside the institution. For those with ambitious career goals including those with no prior computing experience, inter-disciplinary training will be provided to broaden or strengthen computational or biological expertise. Job # 34109 is immediately available to join our scientific visualization team to design and implement novel features and to expand the data content for our pediatric cancer genomic data portal initiative (https://pecan.stjude.org/proteinpaint/). Job # 35345 is immediately available to further ongoing research in developing clonal evolution models of pediatric cancer based on the analysis of next-generation sequencing data. Job # 35262 is immediately available to work as part of the NIH-funded Precision Medicine Center established in collaboration with the departments of Pharmaceutical Sciences and Pathology. The fellow will interact with the genomic discovery and visualization team to receive training and contribute new insight in these two areas. For the complete job descriptions and to apply please click on the ''Apply through website'' button and look for the relevant Job ID. [More]
The Institute for Biomedical Engineering – Cell Biology at RWTH Aachen University Medical School is offering a position for a Bioinformatic Scientist (PhD Student or Postdoc; m/f) starting as soon as possible. We offer a position, which is initially limited for 2 years with the option for extension. The salary is based on the German public service salary scale (TV-L). We are analyzing mechanisms of cellular differentiation in various types of stem cells – particularly embryonic stem cells, induced pluripotent stem cells, hematopoetic stem cells, mesenchymal stem cells, and dendritic cells. To this end, we are using own and public datasets that were generated by next generation sequencing (e.g. DNA-Seq, Chip-Seq, RNA-Seq) or microarrays (gene expression arrays and DNA-methylation platforms). The position is for a talented and motivated bioinformatics scientist that interacts closely with Wet-lab scientists of the groups of Prof. Martin Zenke (http://www.molcell.rwth-aachen.de) and Prof. Wolfgang Wagner (www.stemcellbiology.ukaachen.de). Particular focus is on epigenetic changes – e.g. histone modifications or DNA-methylation changes during differentiation, disease and aging. The lab will also validate and address bioinformatics hypotheses by genome editing technologies, such as CRISPR/Cas. Furthermore, bioinformatics research will be performed in collaboration with our colleagues at the IZKF Research Group Computational Biology (Dr. Ivan Costa; http://costalab.org) and the Joined Research Center for Computational Biomedicine at RWTH Aachen University (Professors Andreas Schuppert and Julio Saez-Rodriguez; www.combine.rwth-aachen.de) – thus, there is an excellent environment for your research. [More]
Competitive: Lilly: Eli Lilly and Company is seeking a talented bioinformatics scientist to join the Oncology Bioinformatics team. He or she will work in a dynamic cross Indianapolis, New York [More]
University of Dundee - UK National Phenotypic Screening CentreSalary: Not specified [More]
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