GENOMICS & BIOINFORMATICS SERVICE
Who We Are
Texas A&M AgriLife Genomics and Bioinformatics Service was established thru a mission directive from Dr. Craig Nessler, Director of AgriLife Research to radically improve genomic research across AgriLife, COALS, and the Texas A&M University System, addressing a central and pressing need for access to the latest genomic technologies, and world-class laboratory and bioinformatics expertise. To meet this ambitious goal, AgriLife Research brought together a team of leading genomics, bioinformatics, molecular, and computational scientists to meet the next generation sequencing (NGS) and bioinformatics needs of the TAMU system and broader scientific community.
The new AgriLife Genomic unit received start-up funds from Texas Emerging Technology Fund as part of a larger AgriLife ETF program under the leadership of Executive Associate Director of Texas A&M AgriLife Research, Dr. Bill McCutchen.
The AgriLife unit is directed by Dr. Charles D. Johnson, who was recruited from the biotech industry to develop a next generation sequencing and bioinformatics program at Texas A&M. With over 20 years of scientific research and operational leadership experience, Dr. Johnson has an established track record in genomics and bioinformatics R&D. He recruited an extraordinary team of Agrilife scientists with vast and diverse background, allowing them to quickly catalyze activity across a broad spectrum of research areas, assuring a high return for each research dollar and generating significant scientific discoveries. The group has built a collaborative network of over 700 scientists spanning the entire TAMU system, along with a growing number of private sector life science and agricultural companies.
Investments in personnel and equipment have been critical to providing genomics and bioinformatics infrastructure for student training, faculty retention and successful R&D initiatives in the areas of agriculture, life sciences, human health, and veterinary medicine.
- AgriLife gets 1st Illumina GAIIx 2009
- AgriLife gets 2nd Illumina GAIIx 2010
- Roche 454 2010
- Illumina HiSeq 2000 purchase Spring 2012
- Illumina HiSeq 2500v3 upgrade Fall 2012
- Led AgriLife Genomic Seed Grant (470K)
- Started offering Illumina MiSeq Spring 2013
- Board of Regents approved CBGSE August 2013
- Move to Gateway facility January 2014
- Illumina MiSeq January 2014
- Led Texas A&M Genomics Seed Grant program (600K) 2014
- Led Genomics of Plant Water Use Seed Grant (300K) 2014
- Illumina HiSeq 2500v4 Summer 2014
- Oxford Nanopore minION system Fall 2014
- Led Vet school graduate seed grant program fall 2015
- Led Vector Borne Disease Genomic Seed Grant (200K) 2016
- Led Genomics of Plant Water Use Seed Grant (220K) 2016
- Illumina HiSeq 4000 June 2016
- PacBio Sequel Auguest 2016
- OxFord Nanopore minION R9 flowcell
- Led Vet school graduate research grant program fall 2016
- Supported over 1025 researchers drawn from over 35 departments, 10 colleges, and multiple agencies across the Texas A&M System.
- Involved in over 350 state and federal grant submissions, resulting in tens of millions in new funding for scientists across the TAMU system (>$30M to date).
- Launched seven Seed Grant programs- distributing a total of $1.6M in sequencing and bioinformatics services to faculty across the system to generate preliminary data to facilitate outside grant funding. 398 seed grants submitted with over 800 total participants. 81 funded projects, generating $8M in new funding from the first $400k seed grant program.
- Marker Assisted Breeding program
- Launched highly successful genomic seed grant program – produced largest response in AgriLife history
Our Vision: Become the leading genomic and bioinformatics academic service provider through superior quality service, innovation, and technical excellence.
Our Values: At the heart of everything we do are our values
Service Obsessed: Dedication to every client’s success. Striving to exceed expectation on a daily basis and provide the best serve possible. Trust and personal responsibility in all relationships.
Problem Solvers: Let us sweat the details, we’ll make it happen and not give up!” Problems are to be solved and only viewed as temporary obstacles. Innovation that matters, for TAMUS, Texas & the World.
Excellence and Pride: We strive to be the best at what we do.
Fun and Creativity: Working hard comes naturally, but fun and creativity is cultivated and protected.
Association Analyses of Genotypes and Phenotypes Using GAPIT and TASSEL 5.0 Thursday, January 12, 1:00-5:00 PM; Heep Center 440 “Association Analyses of Genotypes and Phenotypes Using GAPIT and TASSEL 5.0” Presented By: Dr. Shichen Wang Bioinformatics Scientist, Texas A&M AgriLife Research Shichen Wang is a Bioinformatics Scientist in AgriLife Genomics and Bioinformatics Service. He has Read more about Bioinformatics Workshop – January 12, 2017[…]
2016 was a great year for us. New sequencers and great research, HiSeq 4000, PacBio Sequel, and MinION R9. New website. 365 projects added to our LIMS this year (One a day). Over $1.6M in new grant funding. TxGen is overseeing four genomic seed grant programs.
Our Bioinformatics jobs page has has been totally revamped by Dr. Marcel Brun. We have added the ability to search roles, skills, and by company. This will greatly aid those searching our page. 3265 jobs added to date, over 66 pages of information.
Coming Soon! We will provide with a new form for samples submissions, integrated with our samples management system, to improve greatly the submission part of all projects. The process include: An email with a link and a password, for each project and submission. A login page for the user to log in with the provided Read more about New Web Based Sample Submission Coming Soon[…]
Texas A&M AgriLife Genomics and Bioinformatics Services Facility launches new website with new single page format optimized for smart phones, tablets, and laptop computes. Currently offering Illumina, PacBio and Oxford Nanopore sequencing.
XSEDE team speeds evaluations of transcriptome reconstruction, which will aid our understanding of cellular changes. Scientists hope to establish best practices that will help other researchers find clues to how cells change their behavior in response to disease processes …. “It’s crucial to determine the important factors that affect transcriptome reconstruction,” says Noushin Ghaffari of Read more about Opening the spigot at XSEDE[…]
Dear all, I will teach a bioinformatics workshop in mid-May and you are invited to attend. The class will provide an overview of Next Generation Sequencing (NGS) technology, workflow, data format, applications and data analysis pipelines/tools. It also includes a demo of CLC Genomics Workbench software suite. If you are interested to attend, please select Read more about New Bioinformatics Training[…]
Vector-Borne Disease – Genomics Seed Grant RFP Dear Texas A&M AgriLife Faculty, Texas A&M AgriLife Research is helping lead the effort to expand research for insect-vector borne diseases (VBD) around the State of Texas. During the last legislative session in recognition of AgriLife Research’s leadership in VBD research the Texas legislature provided funding toward basic Read more about Vector-Borne Disease – Genomics Seed Grant RFP[…]
Texas A&M AgriLife Research is helping lead the effort to expand research for insect-vector borne diseases (VBD) around the State of Texas. During the last legislative session in recognition of AgriLife Research’s leadership in VBD research the Texas legislature provided funding toward basic and applied research. As part of this effort AgriLife is acquiring a Read more about Over $1,500,000 in new sequencing equipment coming soon![…]
Last spring a videographer from the Texas A&M Department of Electrical and Computer Engineering came and shot in the lab. You can see our staff and equipment in action throughout the video. Link
Names in bold are TxGen personnel – ready to support your next research project and/or grant.
- Heidi M. Blank, Ricardo Perez, Chong He, Nairita Maitra, Richard Metz, Joshua Hill, Yuhong Lin, Charles D. Johnson, Vytas A. Bankaitis, Brian K. Kennedy, Rodolfo Aramayo and Michael Polymenis. Translational control of lipogenic enzymes in the cell cycle of synchronous, growing yeast cells. 2017 DOI 10.15252/embj.201695050 | Published online 05.01.2017 The EMBO Journal (2017) e201695050 (Article ID: EMBJ788)
- Noushin Ghaffari, Jordi Abante, Raminder Singh, Philip D. Blood, Charles D. Johnson. Computational Considerations in Transcriptome Assemblies and Their Evaluation, using High Quality Human RNA-Seq data July 17 – 21, 2016 ISBN: 978-1-4503-4755-6
- NH Ing, K Konganti, N Ghaffari, CD Johnson, DW Forrest, CC Love, DD Varner. Sequencing of RNA from stallion sperm identifies potential markers of fertility. 2016 Journal of Equine Veterinary Science, S56eS82
- Maria F. Torres, Noushin Ghaffari, Ester A. S. Buiate, Neil Moore, Scott Schwartz, Charles D. Johnson and Lisa J. Vaillancourt. Colletotrichum graminicola mutant deficient in the establishment of biotrophy reveals early transcriptional events in the maize anthracnose disease interaction. BMC Genomics 201617:202. DOI:10.1186/s12864-016-2546-0. 8 March 2016
- Tiwari VK, Heesacker A, Riera-Lizarazu O, Gunn H, Wang S, Wang Y, et al. A whole-genome, radiation hybrid mapping resource of hexaploid wheat. Plant J. 2016; 86:195–207. http://www.ncbi.nlm.nih.gov/pubmed/26945524
(2015) Northern Bobwhite (Colinus virginianus) Mitochondrial Population Genomics Reveals Structure, Divergence, and Evidence for Heteroplasmy. PLoS ONE 10(12): e0144913. doi: 10.1371/journal.pone.0144913
- Ghaffari, N.; Arshad, O.A.; Jeong, H.; Thiltges, J.; Criscitiello, M.F.; Yoon, Byung-Jun; Datta, A.; Johnson, C.D., “Examining De Novo Transcriptome Assemblies via a Quality Assessment Pipeline,” Computational Biology and Bioinformatics, IEEE/ACM Transactions on , vol.PP, no.99, pp.1,1 doi: 10.1109/TCBB.2015.2446478
- Masoud Toloue , Jan Risinger , Lindsey Renken , Josh Hill , Noushin Ghaffari , Richard P Metz , Charles D. Johnson , Amplicon Based 16S Ribosomal RNA Sequencing and Genus Identification – Mixed Species Plant and Animal Genome XXIII Conference 2015.
- Guttieri MJ, Baenziger PS, Frels K, Carver B, Arnall B, Wang S, et al. Prospects for Selecting Wheat with Increased Zinc and Decreased Cadmium Concentration in Grain. Crop Sci. 2015; 55:1712. https://dl.sciencesocieties.org/publications/cs/abstracts/55/4/1712
- Jordan KW, Wang S*(co-first), Lun Y, Gardiner L-J, MacLachlan R, Hucl P, et al. A haplotype map of allohexaploid wheat reveals distinct patterns of selection on homoeologous genomes. Genome Biol. 2015; 16:48. http://www.ncbi.nlm.nih.gov/pubmed/25886949
- Tiwari VK, Wang S, Danilova T, Koo DH, Vrána J, Kubaláková M, et al. Exploring the tertiary gene pool of bread wheat: sequence assembly and analysis of chromosome 5M(g) of Aegilops geniculata. Plant J. 2015; 84:733–46. http://www.ncbi.nlm.nih.gov/pubmed/26408103
AgriLife Genomics and Bioinformatics Service location
101 Gateway, Suite A
College Station TX 77845
Lab Phone: (979) 862-2143
If you are going south on Highway 6 (from TAMU), take the Nantucket exit and make a U-turn under the bridge to get onto the northbound HW6 feeder road. From the feeder road make a right turn into our complex on the right immediately after passing the business park entrance (Gateway Blvd). We are located in Suite A of this building, which is on the right hand side.
Please park in the front of the building.