Genomics & Bioinformatics Service

Providing Genomics and Bioinformatics Service to the Texas A&M AgriLife, the Texas A&M System, Texas, and the World

To start a sequencing project please contact Dr. Charlie Johnson

GENOMICS & BIOINFORMATICS SERVICE

Providing Next Generation Sequencing and Bioinformatics Services
Go to Sequencing

Sequencing

We have already sequenced more than 100 different species (not counting metagenomic projects), over 1000 samples/month processed and we add about one new project every day.

Go to Library preparation

Library preparation

A key element of NGS is the high-quality library preparation. The protocols and equipment used by our team can accommodate a range of needs.

Go to Bioinformatics Analysis and Processing

Bioinformatics Analysis and Processing

Our quantitative and computational analytical unit sits at the cutting edge of bioinformatics research — we use the latest tools and develop improvements to correct short comings with these tools.

To start a project, contact Dr. Johnson for a quote and make arrangements with Dr. Metz to drop off samples

Who We Are

Established to radically improve genomic research across AgriLife, TAMU, and the Texas A&M University System

Director of Texas A&M AgriLife Research Texas A&M AgriLife Genomics and Bioinformatics Service was established thru a mission directive from Dr. Craig Nessler, Director of AgriLife Research to radically improve genomic research across AgriLife, COALS, and the Texas A&M University System, addressing a central and pressing need for access to the latest genomic technologies, and world-class laboratory and bioinformatics expertise. To meet this ambitious goal, AgriLife Research brought together a team of leading genomics, bioinformatics, molecular, and computational scientists to meet the next generation sequencing (NGS) and bioinformatics needs of the TAMU system and broader scientific community.

The new AgriLife Genomic unit received start-up funds from Texas Emerging Technology Fund as part of a larger AgriLife ETF program under the leadership of Executive Associate Director of Texas A&M AgriLife Research, Dr. Bill McCutchen.

Texas A&M AgriLife Director, Genomics and Bioinformatics The AgriLife unit is directed by Dr. Charles D. Johnson, who was recruited from the biotech industry to develop a next generation sequencing and bioinformatics program at Texas A&M. With over 20 years of scientific research and operational leadership experience, Dr. Johnson has an established track record in genomics and bioinformatics R&D. He recruited an extraordinary team of Agrilife scientists with vast and diverse background, allowing them to quickly catalyze activity across a broad spectrum of research areas, assuring a high return for each research dollar and generating significant scientific discoveries. The group has built a collaborative network of over 700 scientists spanning the entire TAMU system, along with a growing number of private sector life science and agricultural companies.

Investments in personnel and equipment have been critical to providing genomics and bioinformatics infrastructure for student training, faculty retention and successful R&D initiatives in the areas of agriculture, life sciences, human health, and veterinary medicine.

    • AgriLife gets 1st Illumina GAIIx 2009
    • AgriLife gets 2nd Illumina GAIIx 2010
    • Roche 454 2010

    • Illumina HiSeq 2000 purchase Spring 2012
    • Illumina HiSeq 2500v3 upgrade Fall 2012
    • Led AgriLife Genomic Seed Grant (470K)
    • Started offering Illumina MiSeq Spring 2013
    • Board of Regents approved CBGSE August 2013
    • Move to Gateway facility January 2014
    • Illumina MiSeq January 2014
    • Led Texas A&M Genomics Seed Grant program (600K) 2014
    • Led Genomics of Plant Water Use Seed Grant (300K) 2014
    • Illumina HiSeq 2500v4 Summer 2014
    • Oxford Nanopore minION system Fall 2014
    • Led Vet school graduate seed grant program fall 2015
    • Led Vector Borne Disease Genomic Seed Grant (200K) 2016
    • Led Genomics of Plant Water Use Seed Grant (220K) 2016
    • Illumina HiSeq 4000 June 2016
    • PacBio Sequel Auguest 2016
    • OxFord Nanopore minION R9 flowcell
    • Led Vet school graduate research grant program fall 2016

    • Supported over 1025 researchers drawn from over 35 departments, 10 colleges, and multiple agencies across the Texas A&M System.
    • Involved in over 350 state and federal grant submissions, resulting in tens of millions in new funding for scientists across the TAMU system (>$30M to date).
    • Launched seven Seed Grant programs- distributing a total of $1.6M in sequencing and bioinformatics services to faculty across the system to generate preliminary data to facilitate outside grant funding. 398 seed grants submitted with over 800 total participants. 81 funded projects, generating $8M in new funding from the first $400k seed grant program.
    • Marker Assisted Breeding program
    • Launched highly successful genomic seed grant program – produced largest response in AgriLife history

Our Vision: Become the leading genomic and bioinformatics academic service provider through superior quality service, innovation, and technical excellence.

Our Values: At the heart of everything we do are our values

Service Obsessed: Dedication to every client’s success. Striving to exceed expectation on a daily basis and provide the best serve possible. Trust and personal responsibility in all relationships.

Problem Solvers: Let us sweat the details, we’ll make it happen and not give up!” Problems are to be solved and only viewed as temporary obstacles. Innovation that matters, for TAMUS, Texas & the World.

Excellence and Pride: We strive to be the best at what we do.

Fun and Creativity: Working hard comes naturally, but fun and creativity is cultivated and protected.

To start a sequencing project please contact Dr. Charlie Johnson

OUR TEAM

The AgriLife unit is directed by Dr. Charles D. Johnson, who recruited an extraordinary team of Agrilife scientists with vast and diverse background, allowing them to quickly catalyze activity across a broad spectrum of research areas.

Joshua Hill, Ph.D.

Sequencing Director
Research Scientist

Joshua.Hill@ag.tamu.edu

Gail Martin, Ph.D.

Unit Admin.
Project Manager

Gail.Martin@ag.tamu.edu

Open Jobs

Systems Administrator
Business manager
Txgen@ag.tamu.edu

To start a project, contact Dr. Johnson for a quote and make arrangements with Dr. Metz to drop off samples

To start a project, contact Dr. Johnson for a quote and make arrangements with Dr. Metz to drop off samples

Names in bold are TxGen personnel – ready to support your next research project and/or grant.

2016

  • Heidi M. Blank, Ricardo Perez, Chong He, Nairita Maitra, Richard Metz, Joshua Hill, Yuhong Lin, Charles D. Johnson, Vytas A. Bankaitis, Brian K. Kennedy, Rodolfo Aramayo and Michael Polymenis.  (accepted for publication Article ID: EMBJ788)
  • Noushin Ghaffari, Jordi Abante, Raminder Singh, Philip D. Blood, Charles D. Johnson. Computational Considerations in Transcriptome Assemblies and Their Evaluation, using High Quality Human RNA-Seq data July 17 – 21, 2016 ISBN: 978-1-4503-4755-6
  • NH Ing, K Konganti, N Ghaffari, CD Johnson, DW Forrest, CC Love, DD Varner. Sequencing of RNA from stallion sperm identifies potential markers of fertility. 2016 Journal of Equine Veterinary Science, S56eS82
  • Maria F. Torres, Noushin Ghaffari, Ester A. S. Buiate, Neil Moore, Scott Schwartz, Charles D. Johnson and Lisa J. Vaillancourt. Colletotrichum graminicola mutant deficient in the establishment of biotrophy reveals early transcriptional events in the maize anthracnose disease interaction. BMC Genomics 201617:202. DOI:10.1186/s12864-016-2546-0. 8 March 2016
  • Tiwari VK, Heesacker A, Riera-Lizarazu O, Gunn H, Wang S, Wang Y, et al. A whole-genome, radiation hybrid mapping resource of hexaploid wheat. Plant J. 2016; 86:195–207.  http://www.ncbi.nlm.nih.gov/pubmed/26945524

2015

  • Yvette A. Halley, David L. Oldeschulte, Eric K. Bhattarai, Joshua Hill, Richard P. Metz, Charles D. Johnson, Steven M. Presley, Rebekah E. Ruzicka, Dale Rollins, Markus J. Peterson, William J. Murphy, Christopher M. Seabury. (2015) Northern Bobwhite (Colinus virginianus) Mitochondrial Population Genomics Reveals Structure, Divergence, and Evidence for Heteroplasmy. PLoS ONE 10(12): e0144913. doi: 10.1371/journal.pone.0144913
  • Ghaffari, N.; Arshad, O.A.; Jeong, H.; Thiltges, J.; Criscitiello, M.F.; Yoon, Byung-Jun; Datta, A.; Johnson, C.D., “Examining De Novo Transcriptome Assemblies via a Quality Assessment Pipeline,” Computational Biology and Bioinformatics, IEEE/ACM Transactions on , vol.PP, no.99, pp.1,1 doi: 10.1109/TCBB.2015.2446478
  • Masoud Toloue , Jan Risinger , Lindsey Renken , Josh Hill , Noushin Ghaffari , Richard P Metz , Charles D. Johnson , Amplicon Based 16S Ribosomal RNA Sequencing and Genus Identification – Mixed Species Plant and Animal Genome XXIII Conference 2015.
  • Guttieri MJ, Baenziger PS, Frels K, Carver B, Arnall B, Wang S, et al. Prospects for Selecting Wheat with Increased Zinc and Decreased Cadmium Concentration in Grain. Crop Sci. 2015; 55:1712.  https://dl.sciencesocieties.org/publications/cs/abstracts/55/4/1712
  • Jordan KW, Wang S*(co-first), Lun Y, Gardiner L-J, MacLachlan R, Hucl P, et al. A haplotype map of allohexaploid wheat reveals distinct patterns of selection on homoeologous genomes. Genome Biol. 2015; 16:48. http://www.ncbi.nlm.nih.gov/pubmed/25886949
  • Tiwari VK, Wang S, Danilova T, Koo DH, Vrána J, Kubaláková M, et al. Exploring the tertiary gene pool of bread wheat: sequence assembly and analysis of chromosome 5M(g) of Aegilops geniculata. Plant J. 2015; 84:733–46. http://www.ncbi.nlm.nih.gov/pubmed/26408103

More Publications

To start a sequencing project please contact Dr. Charlie Johnson

Untitled2AgriLife Genomics and Bioinformatics Service location

Address:
101 Gateway, Suite A
College Station TX 77845

Lab Phone: (979) 862-2143

If you are going south on Highway 6 (from TAMU), take the Nantucket exit and make a U-turn under the bridge to get onto the northbound  HW6 feeder road. From the feeder road make a right turn into our complex on the right immediately after passing the business park entrance (Gateway Blvd). We are located in Suite A of this building, which is on the right hand side.

Please park in the front of the building. 

Directions to new location

To start a project, contact Dr. Johnson for a quote and make arrangements with Dr. Metz to drop off samples